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Nanosecond Dynamics Regulate the MIF-Induced Activity of CD74
Macrophage migration inhibitory factor (MIF) activates CD74, which leads to severe disorders including inflammation, autoimmune diseases and cancer under pathological conditions. Molecular dynamics (MD) simulations up to one microsecond revealed dynamical correlation between a residue located at the...
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| Gepubliceerd in: | Angew Chem Int Ed Engl |
|---|---|
| Hoofdauteurs: | , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6282165/ https://ncbi.nlm.nih.gov/pubmed/29669180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201803191 |
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