GDF-5 can act as a context-dependent BMP-2 antagonist

BACKGROUND: Bone morphogenetic protein (BMP)-2 and growth and differentiation factor (GDF)-5 are two related transforming growth factor (TGF)-β family members with important functions in embryonic development and tissue homeostasis. BMP-2 is best known for its osteoinductive properties whereas GDF-5...

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Detalhes bibliográficos
Publicado no:BMC Biol
Main Authors: Klammert, Uwe, Mueller, Thomas D., Hellmann, Tina V., Wuerzler, Kristian K., Kotzsch, Alexander, Schliermann, Anna, Schmitz, Werner, Kuebler, Alexander C., Sebald, Walter, Nickel, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575486/
https://ncbi.nlm.nih.gov/pubmed/26385096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-015-0183-8
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