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Biological activity of a genetically modified BMP-2 variant with inhibitory activity
BACKGROUND: Alterations of the binding epitopes of bone morphogenetic protein-2 (BMP-2) lead to a modified interaction with the ectodomains of BMP receptors. In the present study the biological effect of a BMP-2 double mutant with antagonistic activity was evaluated in vivo. METHODS: Equine-derived...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2646720/ https://ncbi.nlm.nih.gov/pubmed/19187528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-160X-5-6 |
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