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BMP-2 antagonists emerge from alterations in the low-affinity binding epitope for receptor BMPR-II
Bone morphogenetic protein-2 (BMP-2) induces bone formation and regeneration in adult vertebrates and regulates important developmental processes in all animals. BMP-2 is a homodimeric cysteine knot protein that, as a member of the transforming growth factor-β (TGF-β) superfamily, signals by oligome...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC313944/ https://ncbi.nlm.nih.gov/pubmed/10880444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.13.3314 |
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