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Nanoscale structure of the BMP antagonist chordin supports cooperative BMP binding
Bone morphogenetic proteins (BMPs) orchestrate key cellular events, such as proliferation and differentiation, in development and homeostasis. Extracellular antagonists, such as chordin, are essential regulators of BMP signaling. Chordin binds to BMPs blocking interaction with receptors, and cleavag...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4246984/ https://ncbi.nlm.nih.gov/pubmed/25157165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1404166111 |
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