Structural characterization of twisted gastrulation provides insights into opposing functions on the BMP signalling pathway

Twisted gastrulation (Tsg) and chordin are secreted glycoproteins that function together as BMP (bone morphogenetic protein) antagonists to regulate BMP growth factor signalling. Chordin binds to BMPs, preventing them from interacting with their receptors and Tsg is known to strengthen this inhibito...

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Vydáno v:Matrix Biol
Hlavní autoři: Troilo, Helen, Barrett, Anne L., Zuk, Alexandra V., Lockhart-Cairns, Michael P., Wohl, Alexander P., Bayley, Christopher P., Dajani, Rana, Tunnicliffe, Richard B., Green, Lewis, Jowitt, Thomas A., Sengle, Gerhard, Baldock, Clair
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5080453/
https://ncbi.nlm.nih.gov/pubmed/26829466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2016.01.019
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