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Structural characterization of twisted gastrulation provides insights into opposing functions on the BMP signalling pathway
Twisted gastrulation (Tsg) and chordin are secreted glycoproteins that function together as BMP (bone morphogenetic protein) antagonists to regulate BMP growth factor signalling. Chordin binds to BMPs, preventing them from interacting with their receptors and Tsg is known to strengthen this inhibito...
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Publicado no: | Matrix Biol |
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Main Authors: | , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5080453/ https://ncbi.nlm.nih.gov/pubmed/26829466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2016.01.019 |
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