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The pro-BMP activity of Twisted gastrulation is independent of BMP binding

The determination of the vertebrate dorsoventral body axis is regulated in the extracellular space by a system of interacting secreted molecules consisting of BMP, Chordin, Tolloid and Twisted Gastrulation (Tsg). Tsg is a BMP-binding protein that forms ternary complexes with BMP and Chordin. We inve...

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Detalhes bibliográficos
Main Authors: Oelgeschläger, Michael, Reversade, Bruno, Larraín, Juan, Little, Shawn, Mullins, Mary C., De Robertis, E. M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2277362/
https://ncbi.nlm.nih.gov/pubmed/12874126
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