Glycosylation of Twisted Gastrulation is Required for BMP Binding and Activity during Craniofacial Development

Twisted gastrulation (TWSG1) is a conserved, secreted glycoprotein that modulates signaling of bone morphogenetic proteins (BMPs) in the extracellular space. Deletion of exon 4 of mouse Twsg1 (mTwsg1) is associated with significant craniofacial defects. However, little is understood about the bioche...

詳細記述

保存先:
書誌詳細
主要な著者: Billington, Charles J., Fiebig, Juliane E., Forsman, Cynthia L., Pham, Lan, Burbach, Nathan, Sun, Mu, Jaskoll, Tina, Mansky, Kim, Gopalakrishnan, Rajaram, O’Connor, Michael B., Mueller, Thomas D., Petryk, Anna
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Research Foundation 2011
主題:
Physiology
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170884/
https://ncbi.nlm.nih.gov/pubmed/21941513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2011.00059
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