The role of chordin fragments generated by partial tolloid cleavage in regulating BMP activity

Chordin-mediated regulation of bone morphogenetic protein (BMP) family growth factors is essential in early embryogenesis and adult homoeostasis. Chordin binds to BMPs through cysteine-rich von Willebrand factor type C (vWC) homology domains and blocks them from interacting with their cell surface r...

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Udgivet i:Biochem Soc Trans
Main Authors: Troilo, Helen, Barrett, Anne L., Wohl, Alexander P., Jowitt, Thomas A., Collins, Richard F., Bayley, Christopher P., Zuk, Alexandra V., Sengle, Gerhard, Baldock, Clair
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Ltd. 2015
Fag:
Biochemical Society Focused Meetings
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613500/
https://ncbi.nlm.nih.gov/pubmed/26517884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20150071
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