Extracellular Regulation of Bone Morphogenetic Protein Activity by the Microfibril Component Fibrillin-1

Since the discovery of bone morphogenetic proteins (BMPs) as pluripotent cytokines extractable from bone matrix, it has been speculated how targeting of BMPs to the extracellular matrix (ECM) modulates their bioavailability. Understanding these processes is crucial for elucidating pathomechanisms of...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Wohl, Alexander P., Troilo, Helen, Collins, Richard F., Baldock, Clair, Sengle, Gerhard
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2016
Subjects:
Glycobiology and Extracellular Matrices
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933460/
https://ncbi.nlm.nih.gov/pubmed/27059954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.704734
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