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A Biophysical Approach to Predicting Protein–DNA Binding Energetics

Sequence-specific interactions between proteins and DNA play a central role in DNA replication, repair, recombination, and control of gene expression. These interactions can be studied in vitro using microfluidics, protein-binding microarrays (PBMs), and other high-throughput techniques. Here we dev...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Locke, George, Morozov, Alexandre V.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574261/
https://ncbi.nlm.nih.gov/pubmed/26081193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.178384
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