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Biophysical Fitness Landscapes for Transcription Factor Binding Sites
Phenotypic states and evolutionary trajectories available to cell populations are ultimately dictated by complex interactions among DNA, RNA, proteins, and other molecular species. Here we study how evolution of gene regulation in a single-cell eukaryote S. cerevisiae is affected by interactions bet...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4091707/ https://ncbi.nlm.nih.gov/pubmed/25010228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003683 |
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