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Biophysical Fitness Landscapes for Transcription Factor Binding Sites

Phenotypic states and evolutionary trajectories available to cell populations are ultimately dictated by complex interactions among DNA, RNA, proteins, and other molecular species. Here we study how evolution of gene regulation in a single-cell eukaryote S. cerevisiae is affected by interactions bet...

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Bibliografiske detaljer
Main Authors: Haldane, Allan, Manhart, Michael, Morozov, Alexandre V.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091707/
https://ncbi.nlm.nih.gov/pubmed/25010228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003683
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