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High-throughput sequencing reveals a simple model of nucleosome energetics

We use genome-wide nucleosome maps to study sequence specificity of intrinsic histone-DNA interactions. In contrast with previous approaches, we employ an analogy between a classical one-dimensional fluid of finite-size particles in an arbitrary external potential and arrays of DNA-bound histone oct...

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Autors principals: Locke, George, Tolkunov, Denis, Moqtaderi, Zarmik, Struhl, Kevin, Morozov, Alexandre V.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000311/
https://ncbi.nlm.nih.gov/pubmed/21084631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003838107
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