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Nucleosome depletion at yeast terminators is not intrinsic and can occur by a transcriptional mechanism linked to 3’-end formation

Genome-wide mapping of nucleosomes generated by micrococcal nuclease (MNase) suggests that yeast promoter and terminator regions are very depleted of nucleosomes, predominantly because their DNA sequences intrinsically disfavor nucleosome formation. However, MNase has strong DNA sequence specificity...

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Main Authors: Fan, Xiaochun, Moqtaderi, Zarmik, Jin, Yi, Zhang, Yong, Liu, X. Shirley, Struhl, Kevin
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964211/
https://ncbi.nlm.nih.gov/pubmed/20921369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012674107
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