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Species-specific factors mediate extensive heterogeneity of mRNA 3′ ends in yeasts

Most eukaryotic genes express mRNAs with alternative polyadenylation sites at their 3′ ends. Here we show that polyadenylated 3′ termini in three yeast species (Saccharomyces cerevisiae, Kluyveromyces lactis, and Debaryomyces hansenii) are remarkably heterogeneous. Instead of a few discrete 3′ ends,...

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書誌詳細
主要な著者: Moqtaderi, Zarmik, Geisberg, Joseph V., Jin, Yi, Fan, Xiaochun, Struhl, Kevin
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2013
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703967/
https://ncbi.nlm.nih.gov/pubmed/23776204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1309384110
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