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Species-specific factors mediate extensive heterogeneity of mRNA 3′ ends in yeasts

Most eukaryotic genes express mRNAs with alternative polyadenylation sites at their 3′ ends. Here we show that polyadenylated 3′ termini in three yeast species (Saccharomyces cerevisiae, Kluyveromyces lactis, and Debaryomyces hansenii) are remarkably heterogeneous. Instead of a few discrete 3′ ends,...

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Main Authors: Moqtaderi, Zarmik, Geisberg, Joseph V., Jin, Yi, Fan, Xiaochun, Struhl, Kevin
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703967/
https://ncbi.nlm.nih.gov/pubmed/23776204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1309384110
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