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Species-specific factors mediate extensive heterogeneity of mRNA 3′ ends in yeasts

Most eukaryotic genes express mRNAs with alternative polyadenylation sites at their 3′ ends. Here we show that polyadenylated 3′ termini in three yeast species (Saccharomyces cerevisiae, Kluyveromyces lactis, and Debaryomyces hansenii) are remarkably heterogeneous. Instead of a few discrete 3′ ends,...

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Hlavní autoři: Moqtaderi, Zarmik, Geisberg, Joseph V., Jin, Yi, Fan, Xiaochun, Struhl, Kevin
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703967/
https://ncbi.nlm.nih.gov/pubmed/23776204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1309384110
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