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Species-specific factors mediate extensive heterogeneity of mRNA 3′ ends in yeasts

Most eukaryotic genes express mRNAs with alternative polyadenylation sites at their 3′ ends. Here we show that polyadenylated 3′ termini in three yeast species (Saccharomyces cerevisiae, Kluyveromyces lactis, and Debaryomyces hansenii) are remarkably heterogeneous. Instead of a few discrete 3′ ends,...

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Bibliografski detalji
Glavni autori: Moqtaderi, Zarmik, Geisberg, Joseph V., Jin, Yi, Fan, Xiaochun, Struhl, Kevin
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703967/
https://ncbi.nlm.nih.gov/pubmed/23776204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1309384110
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