Zeta Inhibitory Peptide Disrupts Electrostatic Interactions That Maintain Atypical Protein Kinase C in Its Active Conformation on the Scaffold p62

Atypical protein kinase C (aPKC) enzymes signal on protein scaffolds, yet how they are maintained in an active conformation on scaffolds is unclear. A myristoylated peptide based on the autoinhibitory pseudosubstrate fragment of the atypical PKCζ, zeta inhibitory peptide (ZIP), has been extensively...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Tsai, Li-Chun Lisa, Xie, Lei, Dore, Kim, Xie, Li, Del Rio, Jason C., King, Charles C., Martinez-Ariza, Guillermo, Hulme, Christopher, Malinow, Roberto, Bourne, Philip E., Newton, Alexandra C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571940/
https://ncbi.nlm.nih.gov/pubmed/26187466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.676221
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados