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Conformational signaling required for synaptic plasticity by the NMDA receptor complex

The NMDA receptor (NMDAR) is known to transmit important information by conducting calcium ions. However, some recent studies suggest that activation of NMDARs can trigger synaptic plasticity in the absence of ion flow. Does ligand binding transmit information to signaling molecules that mediate syn...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Aow, Jonathan, Dore, Kim, Malinow, Roberto
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664326/
https://ncbi.nlm.nih.gov/pubmed/26553983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1520029112
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