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Sequestosome 1/p62, a Scaffolding Protein, Is a Newly Identified Partner of IRS-1 Protein

Defects in the insulin-signaling pathway may lead to the development of skeletal muscle insulin resistance, which is one of the earliest abnormalities detected in individuals with the metabolic syndrome and predisposes them to develop type 2 diabetes. Previous studies have shown that deletion of the...

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Detalhes bibliográficos
Main Authors: Geetha, Thangiah, Zheng, Chen, Vishwaprakash, Nilmini, Broderick, Tom L., Babu, Jeganathan Ramesh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436154/
https://ncbi.nlm.nih.gov/pubmed/22761437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.322404
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