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Sequestosome 1/p62, a Scaffolding Protein, Is a Newly Identified Partner of IRS-1 Protein

Defects in the insulin-signaling pathway may lead to the development of skeletal muscle insulin resistance, which is one of the earliest abnormalities detected in individuals with the metabolic syndrome and predisposes them to develop type 2 diabetes. Previous studies have shown that deletion of the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Geetha, Thangiah, Zheng, Chen, Vishwaprakash, Nilmini, Broderick, Tom L., Babu, Jeganathan Ramesh
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436154/
https://ncbi.nlm.nih.gov/pubmed/22761437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.322404
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