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Protein Scaffolds Control Localized Protein Kinase Cζ Activity

Atypical protein kinase C (aPKC) isozymes modulate insulin signaling and cell polarity, but how their activity is controlled in cells is not well understood. These enzymes are constitutively phosphorylated, insensitive to second messengers, and have relatively low activity. Here we show that protein...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Tobias, Irene S., Newton, Alexandra C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919463/
https://ncbi.nlm.nih.gov/pubmed/27143478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.729483
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