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Protein Scaffolds Control Localized Protein Kinase Cζ Activity
Atypical protein kinase C (aPKC) isozymes modulate insulin signaling and cell polarity, but how their activity is controlled in cells is not well understood. These enzymes are constitutively phosphorylated, insensitive to second messengers, and have relatively low activity. Here we show that protein...
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| Veröffentlicht in: | J Biol Chem |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4919463/ https://ncbi.nlm.nih.gov/pubmed/27143478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.729483 |
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