Cellular Pharmacology of Protein Kinase Mζ (PKMζ) Contrasts with Its in Vitro Profile: IMPLICATIONS FOR PKMζ AS A MEDIATOR OF MEMORY

A number of recent studies have used pharmacological inhibitors to establish a role for protein kinase Mζ (PKMζ) in synaptic plasticity and memory. These studies use zeta inhibitory peptide (ZIP) and chelerythrine as inhibitors of PKMζ to block long term potentiation and memory; staurosporine is use...

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Detalhes bibliográficos
Main Authors: Wu-Zhang, Alyssa X., Schramm, Cicely L., Nabavi, Sadegh, Malinow, Roberto, Newton, Alexandra C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339930/
https://ncbi.nlm.nih.gov/pubmed/22378786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.357244
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