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The Protein Scaffold NHERF-1 Controls the Amplitude and Duration of Localized Protein Kinase D Activity
Protein kinase D (PKD) transduces an abundance of signals downstream of diacylglycerol production. The mammalian PKD family consists of three isoforms, PKD1, PKD2, and PKD3; of these PKD1 and PKD2 contain PDZ-binding motifs at their carboxyl termini. Here we show that membrane-localized NHERF scaffo...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2782054/ https://ncbi.nlm.nih.gov/pubmed/19581308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.024547 |
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