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Nicotinic Acetylcholine Receptors Sensitize a MAPK-linked Toxicity Pathway on Prolonged Exposure to β-Amyloid

Among putative downstream synaptic targets of β-amyloid (Aβ) are signaling molecules involved in synaptic function, memory formation and cognition, such as the MAP kinases, MKPs, CaMKII, CREB, Fyn, and Tau. Here, we assessed the activation and interaction of signaling pathways upon prolonged exposur...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Arora, Komal, Cheng, Justin, Nichols, Robert A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571869/
https://ncbi.nlm.nih.gov/pubmed/26139609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.634162
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