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Impact of Sustained Exposure to β-Amyloid on Calcium Homeostasis and Neuronal Integrity in Model Nerve Cell System Expressing α4β2 Nicotinic Acetylcholine Receptors

Although the interaction between β-amyloid (Aβ) and nicotinic acetylcholine receptors has been widely studied, the impact of prolonged exposure to Aβ on nAChR expression and signaling is not known. In this study, we employed a neuronal culture model to better understand the impact of sustained expos...

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Detalhes bibliográficos
Main Authors: Arora, Komal, Alfulaij, Naghum, Higa, Jason K., Panee, Jun, Nichols, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630845/
https://ncbi.nlm.nih.gov/pubmed/23479730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.453746
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