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Nicotinic Acetylcholine Receptors Sensitize a MAPK-linked Toxicity Pathway on Prolonged Exposure to β-Amyloid

Among putative downstream synaptic targets of β-amyloid (Aβ) are signaling molecules involved in synaptic function, memory formation and cognition, such as the MAP kinases, MKPs, CaMKII, CREB, Fyn, and Tau. Here, we assessed the activation and interaction of signaling pathways upon prolonged exposur...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Arora, Komal, Cheng, Justin, Nichols, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571869/
https://ncbi.nlm.nih.gov/pubmed/26139609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.634162
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