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Formation of a Novel Macrocyclic Alkaloid from the Unnatural Farnesyl Diphosphate Analogue Anilinogeranyl Diphosphate by 5-Epi-Aristolochene Synthase

As part of an effort to identify substrate analogs suitable for helping to resolve structural features important for terpene synthases, the inhibition of 5-epi-aristolochene biosynthesis from farnesyl diphosphate (FPP) by the tobacco 5-epi-aristolochene synthase incubated with anilinogeranyl diphosp...

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Détails bibliographiques
Publié dans:ACS Chem Biol
Auteurs principaux: Rising, Kathleen A., Crenshaw, Charisse M., Koo, Hyun Jo, Subramanian, Thangaiah, Chehade, Kareem A. H., Starks, Courtney, Allen, Keith D., Andres, Douglas A., Spielmann, H. Peter, Noel, Joseph P., Chappell, Joe
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570970/
https://ncbi.nlm.nih.gov/pubmed/25897591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00145
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