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X-ray Crystal Structure of Aristolochene Synthase from Aspergillus terreus and the Evolution of Templates for the Cyclization of Farnesyl Diphosphate

Aristolochene synthase from Aspergillus terreus catalyzes the cyclization of the universal sesquiterpene precursor, farnesyl diphosphate, to form the bicyclic hydrocarbon aristolochene. The 2.2 Å resolution X-ray crystal structure of aristolochene synthase reveals a tetrameric quaternary structure i...

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Autors principals: Shishova, Ekaterina Y., Di Costanzo, Luigi, Cane, David E., Christianson, David W.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518937/
https://ncbi.nlm.nih.gov/pubmed/17261032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0622524
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