X-ray Crystal Structure of Aristolochene Synthase from Aspergillus terreus and the Evolution of Templates for the Cyclization of Farnesyl Diphosphate

Aristolochene synthase from Aspergillus terreus catalyzes the cyclization of the universal sesquiterpene precursor, farnesyl diphosphate, to form the bicyclic hydrocarbon aristolochene. The 2.2 Å resolution X-ray crystal structure of aristolochene synthase reveals a tetrameric quaternary structure i...

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Bibliographic Details
Main Authors: Shishova, Ekaterina Y., Di Costanzo, Luigi, Cane, David E., Christianson, David W.
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518937/
https://ncbi.nlm.nih.gov/pubmed/17261032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0622524
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