Formation of a Novel Macrocyclic Alkaloid from the Unnatural Farnesyl Diphosphate Analogue Anilinogeranyl Diphosphate by 5-Epi-Aristolochene Synthase

As part of an effort to identify substrate analogs suitable for helping to resolve structural features important for terpene synthases, the inhibition of 5-epi-aristolochene biosynthesis from farnesyl diphosphate (FPP) by the tobacco 5-epi-aristolochene synthase incubated with anilinogeranyl diphosp...

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Bibliografiska uppgifter
I publikationen:ACS Chem Biol
Huvudupphovsmän: Rising, Kathleen A., Crenshaw, Charisse M., Koo, Hyun Jo, Subramanian, Thangaiah, Chehade, Kareem A. H., Starks, Courtney, Allen, Keith D., Andres, Douglas A., Spielmann, H. Peter, Noel, Joseph P., Chappell, Joe
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570970/
https://ncbi.nlm.nih.gov/pubmed/25897591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00145
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