Formation of a Novel Macrocyclic Alkaloid from the Unnatural Farnesyl Diphosphate Analogue Anilinogeranyl Diphosphate by 5-Epi-Aristolochene Synthase

As part of an effort to identify substrate analogs suitable for helping to resolve structural features important for terpene synthases, the inhibition of 5-epi-aristolochene biosynthesis from farnesyl diphosphate (FPP) by the tobacco 5-epi-aristolochene synthase incubated with anilinogeranyl diphosp...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Rising, Kathleen A., Crenshaw, Charisse M., Koo, Hyun Jo, Subramanian, Thangaiah, Chehade, Kareem A. H., Starks, Courtney, Allen, Keith D., Andres, Douglas A., Spielmann, H. Peter, Noel, Joseph P., Chappell, Joe
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570970/
https://ncbi.nlm.nih.gov/pubmed/25897591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00145
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