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Copy number alterations detected by whole-exome and whole-genome sequencing of esophageal adenocarcinoma

BACKGROUND: Esophageal adenocarcinoma (EA) is among the leading causes of cancer mortality, especially in developed countries. A high level of somatic copy number alterations (CNAs) accumulates over the decades in the progression from Barrett’s esophagus, the precursor lesion, to EA. Accurate identi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Hum Genomics
Hauptverfasser: Wang, Xiaoyu, Li, Xiaohong, Cheng, Yichen, Sun, Xin, Sun, Xibin, Self, Steve, Kooperberg, Charles, Dai, James Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570720/
https://ncbi.nlm.nih.gov/pubmed/26374103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-015-0044-0
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