Whole-genome sequencing of esophageal adenocarcinoma in Chinese patients reveals distinct mutational signatures and genomic alterations

While the incidence of esophageal adenocarcinoma (EAC) has risen drastically in Western countries over the last 40 years, a similar trend has not been observed for EAC in China. Here, we analyzed mutational spectrum, copy number alterations, and structural variants from whole-genome sequencing of 10...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Dai, James Y., Wang, Xiaoyu, Buas, Matthew F., Zhang, Chengjuan, Ma, Jie, Wei, Bing, Li, Yin, Zhao, Baosheng, Hyun, Teresa S., Chen, Xueyan, Loeb, Keith R., Odze, Robert, Yao, Lena, Sun, Xin, Self, Steve, Vaughan, Thomas L., Guo, Yongjun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6200836/
https://ncbi.nlm.nih.gov/pubmed/30374464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-018-0182-8
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