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Whole-Exome Sequencing Characterizes the Landscape of Somatic Mutations and Copy Number Alterations in Adrenocortical Carcinoma

CONTEXT: Adrenocortical carcinoma (ACC) is a rare and lethal malignancy with a poorly defined etiology, and the molecular genetics of ACC are incompletely understood. OBJECTIVE: To utilize whole-exome sequencing for genetic characterization of the underlying somatic mutations and copy number alterat...

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Bibliografske podrobnosti
izdano v:J Clin Endocrinol Metab
Main Authors: Juhlin, C. Christofer, Goh, Gerald, Healy, James M., Fonseca, Annabelle L., Scholl, Ute I., Stenman, Adam, Kunstman, John W., Brown, Taylor C., Overton, John D., Mane, Shrikant M., Nelson-Williams, Carol, Bäckdahl, Martin, Suttorp, Anna-Carinna, Haase, Matthias, Choi, Murim, Schlessinger, Joseph, Rimm, David L., Höög, Anders, Prasad, Manju L., Korah, Reju, Larsson, Catharina, Lifton, Richard P., Carling, Tobias
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393505/
https://ncbi.nlm.nih.gov/pubmed/25490274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-3282
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