Characterization of the mutational landscape of anaplastic thyroid cancer via whole-exome sequencing

Anaplastic thyroid carcinoma (ATC) is a frequently lethal malignancy that is often unresponsive to available therapeutic strategies. The tumorigenesis of ATC and its relationship to the widely prevalent well-differentiated thyroid carcinomas are unclear. We have analyzed 22 cases of ATC as well as 4...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Kunstman, John W., Juhlin, C. Christofer, Goh, Gerald, Brown, Taylor C., Stenman, Adam, Healy, James M., Rubinstein, Jill C., Choi, Murim, Kiss, Nimrod, Nelson-Williams, Carol, Mane, Shrikant, Rimm, David L., Prasad, Manju L., Höög, Anders, Zedenius, Jan, Larsson, Catharina, Korah, Reju, Lifton, Richard P., Carling, Tobias
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380073/
https://ncbi.nlm.nih.gov/pubmed/25576899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu749
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