Načítá se...

An ALS disease mutation in Cdc48/p97 impairs 20S proteasome binding and proteolytic communication

Cdc48 (also known as p97 or VCP) is an essential and highly abundant, double-ring AAA+ ATPase, which is ubiquitous in archaea and eukaryotes. In archaea, Cdc48 ring hexamers play a direct role in quality control by unfolding and translocating protein substrates into the degradation chamber of the 20...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Protein Sci
Hlavní autoři: Barthelme, Dominik, Jauregui, Ruben, Sauer, Robert T
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Ltd 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570545/
https://ncbi.nlm.nih.gov/pubmed/26134898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2740
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!