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Origin and functional evolution of the Cdc48/p97/VCP AAA+ protein unfolding and remodeling machine

The AAA+ Cdc48 ATPase (alias p97 or VCP) is a key player in multiple ubiquitin-dependent cell signaling, degradation, and quality-control pathways. Central to these broad biological functions is the ability of Cdc48 to interact with a large number of adaptor proteins and to remodel macromolecular pr...

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Bibliografske podrobnosti
izdano v:J Mol Biol
Main Authors: Barthelme, Dominik, Sauer, Robert T.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860136/
https://ncbi.nlm.nih.gov/pubmed/26608813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.11.015
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