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Strain-Dependent Effect of Macroautophagy on Abnormally Folded Prion Protein Degradation in Infected Neuronal Cells
Prion diseases are neurodegenerative disorders caused by the accumulation of abnormal prion protein (PrP(Sc)) in the central nervous system. With the aim of elucidating the mechanism underlying the accumulation and degradation of PrP(Sc), we investigated the role of autophagy in its degradation, usi...
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| Vydáno v: | PLoS One |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4569470/ https://ncbi.nlm.nih.gov/pubmed/26368533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137958 |
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