Strain-Dependent Effect of Macroautophagy on Abnormally Folded Prion Protein Degradation in Infected Neuronal Cells

Prion diseases are neurodegenerative disorders caused by the accumulation of abnormal prion protein (PrP(Sc)) in the central nervous system. With the aim of elucidating the mechanism underlying the accumulation and degradation of PrP(Sc), we investigated the role of autophagy in its degradation, usi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Ishibashi, Daisuke, Homma, Takujiro, Nakagaki, Takehiro, Fuse, Takayuki, Sano, Kazunori, Takatsuki, Hanae, Atarashi, Ryuichiro, Nishida, Noriyuki
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2015
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569470/
https://ncbi.nlm.nih.gov/pubmed/26368533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137958
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