Distribution of GNAQ and GNA11 Mutation Signatures in Uveal Melanoma Points to a Light Dependent Mutation Mechanism

Uveal melanomas (UM) originate from melanocytes in the interior wall of the eye, namely from the iris, ciliary body and the choroid with marked differences in light exposure (from dark anterior to illuminated posterior). In contrast to UV radiation, focused or converging visible light readily reache...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: de Lange, Mark J., Razzaq, Lubna, Versluis, Mieke, Verlinde, Sven, Dogrusöz, Mehmet, Böhringer, Stefan, Marinkovic, Marina, Luyten, Gregorius P. M., de Keizer, Rob J. W., de Gruijl, Frank R., Jager, Martine J., van der Velden, Pieter A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2015
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569098/
https://ncbi.nlm.nih.gov/pubmed/26368812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138002
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