IP3R deficit underlies loss of salivary fluid secretion in Sjögren’s Syndrome

The autoimmune exocrinopathy, Sjögren’s syndrome (SS), is associated with secretory defects in patients, including individuals with mild lymphocytic infiltration and minimal glandular damage. The mechanism(s) underlying the secretory dysfunction is not known. We have used minor salivary gland biopsi...

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Publicado en:Sci Rep
Autores principales: Teos, Leyla Y., Zhang, Yu, Cotrim, Ana P., Swaim, William, Won, Jon H., Ambrus, Julian, Shen, Long, Bebris, Lolita, Grisius, Margaret, Jang, Shyh-Ing, Yule, David I., Ambudkar, Indu S., Alevizos, Ilias
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568516/
https://ncbi.nlm.nih.gov/pubmed/26365984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13953
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