IP3R deficit underlies loss of salivary fluid secretion in Sjögren’s Syndrome

The autoimmune exocrinopathy, Sjögren’s syndrome (SS), is associated with secretory defects in patients, including individuals with mild lymphocytic infiltration and minimal glandular damage. The mechanism(s) underlying the secretory dysfunction is not known. We have used minor salivary gland biopsi...

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Publicat a:Sci Rep
Autors principals: Teos, Leyla Y., Zhang, Yu, Cotrim, Ana P., Swaim, William, Won, Jon H., Ambrus, Julian, Shen, Long, Bebris, Lolita, Grisius, Margaret, Jang, Shyh-Ing, Yule, David I., Ambudkar, Indu S., Alevizos, Ilias
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568516/
https://ncbi.nlm.nih.gov/pubmed/26365984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13953
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