IP3R deficit underlies loss of salivary fluid secretion in Sjögren’s Syndrome

The autoimmune exocrinopathy, Sjögren’s syndrome (SS), is associated with secretory defects in patients, including individuals with mild lymphocytic infiltration and minimal glandular damage. The mechanism(s) underlying the secretory dysfunction is not known. We have used minor salivary gland biopsi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Teos, Leyla Y., Zhang, Yu, Cotrim, Ana P., Swaim, William, Won, Jon H., Ambrus, Julian, Shen, Long, Bebris, Lolita, Grisius, Margaret, Jang, Shyh-Ing, Yule, David I., Ambudkar, Indu S., Alevizos, Ilias
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568516/
https://ncbi.nlm.nih.gov/pubmed/26365984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13953
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