IP3R deficit underlies loss of salivary fluid secretion in Sjögren’s Syndrome

The autoimmune exocrinopathy, Sjögren’s syndrome (SS), is associated with secretory defects in patients, including individuals with mild lymphocytic infiltration and minimal glandular damage. The mechanism(s) underlying the secretory dysfunction is not known. We have used minor salivary gland biopsi...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Teos, Leyla Y., Zhang, Yu, Cotrim, Ana P., Swaim, William, Won, Jon H., Ambrus, Julian, Shen, Long, Bebris, Lolita, Grisius, Margaret, Jang, Shyh-Ing, Yule, David I., Ambudkar, Indu S., Alevizos, Ilias
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568516/
https://ncbi.nlm.nih.gov/pubmed/26365984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13953
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