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Up-regulation of Store-operated Ca(2+) Entry and Nuclear Factor of Activated T Cells Promote the Acinar Phenotype of the Primary Human Salivary Gland Cells

The signaling pathways involved in the generation and maintenance of exocrine gland acinar cells have not yet been established. Primary human salivary gland epithelial cells, derived from salivary gland biopsies, acquired an acinar-like phenotype when the [Ca(2+)] in the serum-free medium (keratinoc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Jang, Shyh-Ing, Ong, Hwei Ling, Liu, Xibao, Alevizos, Ilias, Ambudkar, Indu S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861440/
https://ncbi.nlm.nih.gov/pubmed/26903518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.701607
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