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Iron misregulation and neurodegenerative disease in mouse models that lack iron regulatory proteins

Iron regulatory proteins 1 and 2 (IRP1 and IRP2) are two cytosolic proteins that maintain cellular iron homeostasis by binding to RNA stem loops known as iron responsive elements (IREs) that are found in the untranslated regions of target mRNAs that encode proteins involved in iron metabolism. IRPs...

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Bibliografische gegevens
Gepubliceerd in:Neurobiol Dis
Hoofdauteurs: Ghosh, Manik C., Zhang, De-Liang, Rouault, Tracey A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567523/
https://ncbi.nlm.nih.gov/pubmed/25771171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2015.02.026
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