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The physiological functions of iron regulatory proteins in iron homeostasis - an update
Iron regulatory proteins (IRPs) regulate the expression of genes involved in iron metabolism by binding to RNA stem-loop structures known as iron responsive elements (IREs) in target mRNAs. IRP binding inhibits the translation of mRNAs that contain an IRE in the 5′untranslated region of the transcri...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4056636/ https://ncbi.nlm.nih.gov/pubmed/24982634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00124 |
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