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Iron misregulation and neurodegenerative disease in mouse models that lack iron regulatory proteins

Iron regulatory proteins 1 and 2 (IRP1 and IRP2) are two cytosolic proteins that maintain cellular iron homeostasis by binding to RNA stem loops known as iron responsive elements (IREs) that are found in the untranslated regions of target mRNAs that encode proteins involved in iron metabolism. IRPs...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Ghosh, Manik C., Zhang, De-Liang, Rouault, Tracey A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567523/
https://ncbi.nlm.nih.gov/pubmed/25771171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2015.02.026
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