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Iron misregulation and neurodegenerative disease in mouse models that lack iron regulatory proteins
Iron regulatory proteins 1 and 2 (IRP1 and IRP2) are two cytosolic proteins that maintain cellular iron homeostasis by binding to RNA stem loops known as iron responsive elements (IREs) that are found in the untranslated regions of target mRNAs that encode proteins involved in iron metabolism. IRPs...
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Publicado no: | Neurobiol Dis |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4567523/ https://ncbi.nlm.nih.gov/pubmed/25771171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2015.02.026 |
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