Cardiac myosin light chain phosphorylation and inotropic effects of a biased ligand, TRV120023, in a dilated cardiomyopathy model

AIMS: Therapeutic approaches to treat familial dilated cardiomyopathy (DCM), which is characterized by depressed sarcomeric tension and susceptibility to Ca(2+)-related arrhythmias, have been generally unsuccessful. Our objective in the present work was to determine the effect of the angiotensin II...

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Detalles Bibliográficos
Publicado en:Cardiovasc Res
Main Authors: Tarigopula, Madhusudhan, Davis, Robert T., Mungai, Paul T., Ryba, David M., Wieczorek, David F., Cowan, Conrad L., Violin, Jonathan D., Wolska, Beata M., Solaro, R. John
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2015
Assuntos:
Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4565987/
https://ncbi.nlm.nih.gov/pubmed/26045475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvv162
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