Genetic Variation at the LDL Receptor and HMG CoA Reductase Gene Loci, Lipid Levels, Statin Response, and Cardiovascular Disease Incidence in PROSPER

Our purpose was to evaluate associations of single nucleotide polymorphisms (SNPs) at the low density lipoprotein (LDL) receptor (LDLR C44857T, minor allele frequency (MAF) 0.26, and A44964G, MAF 0.25, both in the untranslated region) and HMG-CoA reductase (HMGCR i18T>G, MAF 0.019) gene loci with...

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Publicado en:Atherosclerosis
Autores principales: Polisecki, Eliana, Muallem, Hind, Maeda, Nobuyo, Peter, Inga, Robertson, Michele, McMahon, Alex D, Ford, Ian, Packard, Christopher, Shepherd, James, Jukema, J Wouter, Westendorp, Rudi G. J., de Craen, Anton J. M., Buckley, Brendan M., Ordovas, Jose M., Schaefer, Ernst J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4565152/
https://ncbi.nlm.nih.gov/pubmed/18261733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2007.12.004
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