Genetic Variation at the LDL Receptor and HMG CoA Reductase Gene Loci, Lipid Levels, Statin Response, and Cardiovascular Disease Incidence in PROSPER

Our purpose was to evaluate associations of single nucleotide polymorphisms (SNPs) at the low density lipoprotein (LDL) receptor (LDLR C44857T, minor allele frequency (MAF) 0.26, and A44964G, MAF 0.25, both in the untranslated region) and HMG-CoA reductase (HMGCR i18T>G, MAF 0.019) gene loci with...

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Bibliografske podrobnosti
izdano v:Atherosclerosis
Main Authors: Polisecki, Eliana, Muallem, Hind, Maeda, Nobuyo, Peter, Inga, Robertson, Michele, McMahon, Alex D, Ford, Ian, Packard, Christopher, Shepherd, James, Jukema, J Wouter, Westendorp, Rudi G. J., de Craen, Anton J. M., Buckley, Brendan M., Ordovas, Jose M., Schaefer, Ernst J.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4565152/
https://ncbi.nlm.nih.gov/pubmed/18261733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2007.12.004
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